This is a general question: As we know there are a lot of vanishing theorems like Fujita vanishing, kodaira Nakano vanishing, vanishing for big nef line bundle, Kollár vanishing, etc. Those just for projective guys.

My question is: are there some important vanishing problems for general complete algebraic manifold? Although we don't have nice line bundle like $\mathcal{O}_X(1)$, are there still some vanishing expectation for cohomology of coherent sheaves in some sense.

More specific question, if we have a proper surjective morphism $f:X\rightarrow Y$, $X$ complete, $Y$ projective, do we expect that $R^jf_*\mathcal{O}_X(K_X)=0$ for $j>dim X-dim Y$?